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For the analysis, 21-1 mediation models with random intercepts and fixed slopes were used [35]

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But now we know that e-cigarettes do produce free radicals, and the amount is affected by the flavorants added. Free radicals are unstable molecules that can cause damage to healthy cells, and have been linked to conditions like inflammation, heart disease and cancer

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This change is a clear example of the market's willingness to deliver what the consumers want, namely, the ease of use, and variety in flavor choices, on top